منابع مشابه
Age at diagnosis of diabetes in Appalachia
BACKGROUND Appalachia is a region of the United States noted for the poverty and poor health outcomes of its residents. Residents of the poorest Appalachian counties have a high prevalence of diabetes and risk factors (obesity, low income, low education, etc.) for type 2 diabetes. However, diabetes prevalence exceeds what these risk factors alone explain. Based on this, the history of poor heal...
متن کاملAssociation Between Maternal Diabetes in Utero and Age at Offspring's Diagnosis of Type 2 Diabetes
OBJECTIVE The purpose of this study was to examine age of diabetes diagnosis in youth who have a parent with diabetes by diabetes type and whether the parent's diabetes was diagnosed before or after the youth's birth. RESEARCH DESIGN AND METHODS The cohort comprised SEARCH for Diabetes in Youth Study participants (diabetes diagnosis 2001-2005) with a diabetic parent. SEARCH is a multicenter s...
متن کاملPolygenic modifiers of HNF1A-MODY age at diagnosis Polygenic Risk Variants for Type 2 Diabetes Susceptibility Modify Age at Diagnosis in Monogenic HNF1A Diabetes Short Title: Polygenic modifiers of HNF1A-MODY age at diagnosis
1. Genetics of Complex Traits, Peninsula College of Medicine and Dentistry, Exeter, UK 2. Diabetes Genetics, Peninsula College of Medicine and Dentistry, Exeter, UK 3. Department of Clinical Medicine, University of Bergen, Bergen, Norway 4. Center for Medical Genetics and Molecular Medicine, Haukeland University Hospital, Bergen, Norway 5. Department of Biomedicine, University of Bergen, Bergen...
متن کاملPolygenic Risk Variants for Type 2 Diabetes Susceptibility Modify Age at Diagnosis in Monogenic HNF1A Diabetes
OBJECTIVE Mutations in the HNF1A gene are the most common cause of maturity-onset diabetes of the young (MODY). There is a substantial variation in the age at diabetes diagnosis, even within families where diabetes is caused by the same mutation. We investigated the hypothesis that common polygenic variants that predispose to type 2 diabetes might account for the difference in age at diagnosis....
متن کاملEconomics of adult obesity and diabetes in Appalachia
Obesity and diabetes are major health problems in the United States. The primary aim of this study is to examine the association between obesity and diabetes and to estimate the cost of diabetes linked to obesity in the Appalachian region. A system of simultaneous equations approach, and a logit estimation are employed for the analyses. Behavioral Risk Factor Surveillance System (BRFSS) surveys...
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ژورنال
عنوان ژورنال: Population Health Metrics
سال: 2011
ISSN: 1478-7954
DOI: 10.1186/1478-7954-9-54